Product Name | Rabbit anti-TCF7L1 polyclonal antibody - N-terminal region |
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Antibody Type | Primary Antibodies |
Immunogen |
The immunogen for anti-TCF7L1 antibody: synthetic peptide directed towards the N terminal of human TCF7L1 |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | TCF7L1 |
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Gene Synonyms |
TCF7L1
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Gene Full Name | Transcription factor 7-like 1 (T-cell specific, HMG-box) |
Gene Summary |
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
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Alternative Names |
TCF-3
TCF3 |
Molecular Weight(MW) | 63kDa |
Sequence | 588 amino acids |
Entrez Gene | 83439 |
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SwissProt ID | Q9HCS4 |
Protein Accession | NP_112573 |
Immunohistochemistry with Human Skin lysate tissue at an antibody concentration of 5.0ug/ml using anti-TCF7L1 antibody ()
WB Suggested Anti-TCF7L1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |