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產(chǎn)品名稱(chēng): TCF7L1 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
TCF7L1 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。TCF7L1 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
TCF7L1 antibody
的詳細(xì)介紹
TCF7L1 antibodyProduct Profile
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Product Name
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Rabbit anti-TCF7L1 polyclonal antibody - N-terminal region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-TCF7L1 antibody: synthetic peptide directed towards the N terminal of human TCF7L1
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TCF7L1 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WBIHC
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Species Reactivity
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Guinea PigHumanMouseRabbit
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Concentration
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1mg/ml
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Purification
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Affinity purified
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TCF7L1 antibodyTarget Information
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Gene Symbol
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TCF7L1
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Gene Synonyms
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TCF7L1
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Gene Full Name
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Transcription factor 7-like 1 (T-cell specific, HMG-box)
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Gene Summary
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TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
More
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Alternative Names
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TCF-3
TCF3
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Molecular Weight(MW)
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63kDa
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Sequence
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588 amino acids
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TCF7L1 antibodyDatabase Links
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Entrez Gene
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83439
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SwissProt ID
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Q9HCS4
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Protein Accession
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NP_112573
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TCF7L1 antibodyApplication
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Application
Immunohistochemistry with Human Skin lysate tissue at an antibody concentration of 5.0ug/ml using anti-TCF7L1 antibody ()
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Application
WB Suggested Anti-TCF7L1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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