| Product Name | Rabbit anti-AREG polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen |
The immunogen for anti-AREG antibody: synthetic peptide directed towards the middle region of human AREG |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AREG |
|---|---|
| Gene Synonyms |
AR
AREGB CRDGF MGC13647 SDGF |
| Gene Full Name | Amphiregulin |
| Gene Summary |
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
|
| Alternative Names |
AR
AREGB CRDGF MGC13647 SDGF |
| Molecular Weight(MW) | 28kDa |
| Sequence | 252 amino acids |
| Entrez Gene | 374 |
|---|---|
| SwissProt ID | P15514 |
| Protein Accession | NP_001648 |
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: ACHN cell lysate
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |