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產(chǎn)品名稱: BCL2L1 antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
BCL2L1 antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。BCL2L1 antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
BCL2L1 antibody
的詳細(xì)介紹
BCL2L1 antibodyProduct Profile
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Product Name
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Rabbit anti-BCL2L1 polyclonal antibody - N-terminal region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-BCL2L1 antibody: synthetic peptide directed towards the N terminal of human BCL2L1
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BCL2L1 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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BovineDogHumanMousePigRabbitRatSheep
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Concentration
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1mg/ml
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Purification
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Protein A
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BCL2L1 antibodyTarget Information
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Gene Symbol
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BCL2L1
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Gene Synonyms
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BCL-XL/S
BCL2L
BCLX
Bcl-X
DKFZp781P2092
bcl-xL
bcl-xS
BCLXL
BCLXS
PPP1R52
More
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Gene Full Name
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BCL2-like 1
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Gene Summary
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BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
More
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Alternative Names
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BCL-XL/S
BCL2L
BCLX
Bcl-X
DKFZp781P2092
bcl-xL
bcl-xS
BCLXL
BCLXS
PPP1R52
More
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Molecular Weight(MW)
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26kDa
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Sequence
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233 amino acids
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BCL2L1 antibodyDatabase Links
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Entrez Gene
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598
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SwissProt ID
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Q07817
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Protein Accession
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NP_612815
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BCL2L1 antibodyApplication
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Western blot
2.5ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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