Product Name | Rabbit anti-BAK1 polyclonal antibody - N-terminal region |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | BAK1 |
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Gene Synonyms |
BAK
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BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887 |
Gene Full Name | BCL2-antagonist/killer 1 |
Gene Summary |
BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
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Alternative Names |
BAK
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BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887 |
Molecular Weight(MW) | 23kDa |
Sequence | 211 amino acids |
Entrez Gene | 578 |
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SwissProt ID | Q16611 |
Protein Accession | NP_001179 |
Titration: 1.0 ug/ml
Positive Control: Fetal Heart
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |