Product Name | Rabbit anti-Hand2 polyclonal antibody - C-terminal region |
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Antibody Type | Primary Antibodies |
Immunogen |
The immunogen for anti-Hand2 antibody: synthetic peptide corresponding to a region of Mouse |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | Hand2 |
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Gene Synonyms |
AI225906
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AI661148 Ehand2 Hed Th2 Thing2 bHLHa26 dHAND |
Gene Full Name | Heart and neural crest derivatives expressed transcript 2 |
Gene Summary |
Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
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Alternative Names |
AI225906
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AI661148 Ehand2 Hed Th2 Thing2 bHLHa26 dHAND |
Molecular Weight(MW) | 24kDa |
Sequence | 217 amino acids |
Entrez Gene | 15111 |
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SwissProt ID | Q61039 |
Protein Accession | NP_034532 |
Host: Rabbit
Target Name: Hand2
Sample Tissue: Mouse Heart lysates
Antibody Dilution: 1.0ug/ml
Titration: 1.0 ug/ml
Positive Control: Mouse Heart
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |