Product Name | Rabbit anti-E2F1 polyclonal antibody - middle region |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | E2F1 |
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Gene Synonyms |
E2F-1
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RBAP1 RBBP3 RBP3 |
Gene Full Name | E2F transcription factor 1 |
Gene Summary |
The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
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Alternative Names |
E2F-1
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RBAP1 RBBP3 RBP3 |
Molecular Weight(MW) | 47kDa |
Sequence | 437 amino acids |
Entrez Gene | 1869 |
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SwissProt ID | Q01094 |
Protein Accession | NP_005216 |
Titration: 1.0 ug/ml
Positive Control: Fetal Lung
1. 30 ug Cytosol extract: Untransfected cells 2. 30 ug Cytosol extract: Cells transfected with control (non-targeting) siRNA 3. 30 ug Cytosol extract: Cells transfected with anti-E2F1-siRNA 4. 30 ug Cytosol extract: Cells transfected with anti-E2F1-siRNA
Primary Antibody Dilution:
1:2000
Secondary Antibody:
Goat anti-rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
E2F1
Submitted by:
Ewelina Swiderek, Insitute of Immunology and Experimental Therapy, Wroclaw, Poland
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |