Product Name | Rabbit anti-IRF8 polyclonal antibody - C-terminal region |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | IRF8 |
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Gene Synonyms |
H-ICSBP
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ICSBP ICSBP1 IRF-8 |
Gene Full Name | Interferon regulatory factor 8 |
Gene Summary |
Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
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Alternative Names |
H-ICSBP
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ICSBP ICSBP1 IRF-8 |
Molecular Weight(MW) | 48kDa |
Sequence | 426 amino acids |
Entrez Gene | 3394 |
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SwissProt ID | Q02556 |
Protein Accession | NP_002154 |
Titration: 1.0 ug/ml
Positive Control: THP-1 Whole Cell
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |