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產(chǎn)品名稱: TADA3L antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
TADA3L antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。TADA3L antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
TADA3L antibody
的詳細(xì)介紹
TADA3L antibodyProduct Profile
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Product Name
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Rabbit anti-TADA3L polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-TADA3L antibody: synthetic peptide directed towards the middle region of human TADA3L
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TADA3L antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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Zebra Fish
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Concentration
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1mg/ml
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Purification
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Affinity purified
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TADA3L antibodyTarget Information
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Gene Symbol
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TADA3L
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Gene Synonyms
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ADA3
FLJ20221
FLJ21329
hADA3
NGG1
TADA3L
More
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Gene Full Name
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Transcriptional adaptor 3
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Gene Summary
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Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
More
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Alternative Names
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ADA3
FLJ20221
FLJ21329
hADA3
NGG1
TADA3L
More
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Molecular Weight(MW)
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49kDa
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Sequence
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432 amino acids
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TADA3L antibodyDatabase Links
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Entrez Gene
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10474
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SwissProt ID
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O75528
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Protein Accession
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NP_006345
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TADA3L antibodyApplication
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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