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產(chǎn)品名稱: PPARGC1A antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
PPARGC1A antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。PPARGC1A antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
PPARGC1A antibody
的詳細(xì)介紹
PPARGC1A antibodyProduct Profile
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Product Name
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Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A
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PPARGC1A antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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IFWB
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Species Reactivity
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BovineDogGoatHorseHumanMousePigRabbitRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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PPARGC1A antibodyTarget Information
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Gene Symbol
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PPARGC1A
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Gene Synonyms
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LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
More
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Gene Full Name
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Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
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Gene Summary
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PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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Alternative Names
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LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
More
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Molecular Weight(MW)
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91kDa
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Sequence
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798 amino acids
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PPARGC1A antibodyDatabase Links
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Entrez Gene
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10891
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SwissProt ID
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Q9UBK2
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Protein Accession
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NP_037393
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PPARGC1A antibodyApplication
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Immunofluorescence
Mouse retina
Primary Antibody Dilution :
1:200
Secondary Antibody :
Donkey anti rabbit-Cy3
Secondary Antibody Dilution :
1:1000
Color/Signal Descriptions :
Red: PPARGC1A
Gene Name :
PPARGC1A
Submitted by :
Dr. Joshua Sanes
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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