Product Name | Rabbit anti-RIPK3 polyclonal antibody - N-terminal region |
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Antibody Type | Primary Antibodies |
Immunogen |
The immunogen for anti-RIPK3 antibody: synthetic peptide directed towards the N terminal of human RIPK3 |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Protein A |
Gene Symbol | RIPK3 |
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Gene Synonyms |
RIP3
RIP3 beta RIP3 gamma |
Gene Full Name | Receptor-interacting serine-threonine kinase 3 |
Gene Summary |
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
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Alternative Names |
RIP3
RIP3 beta RIP3 gamma |
Molecular Weight(MW) | 57kDa |
Sequence | 518 amino acids |
Entrez Gene | 11035 |
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SwissProt ID | Q9Y572 |
Protein Accession | NP_006862 |
1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |