Product Name | Rabbit anti-DDIT3 Antibody - N-terminal region |
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Antibody Type | Primary Antibodies |
Immunogen |
The immunogen for Anti-DDIT3 antibody is: synthetic peptide directed towards the N-terminal region of Human DDIT3 |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Gene Symbol | DDIT3 |
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Gene Full Name | DNA-damage-inducible transcript 3 |
Gene Summary |
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
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Molecular Weight(MW) | 21kDa |
Sequence | 192 amino acids |
Entrez Gene | 1649 |
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SwissProt ID | F8VS99 |
Protein Accession | NP_001181985 |
Host: Rabbit
Target Name: DDIT3
Sample Tissue: Stomach Tumor lysates
Antibody Dilution: 1.0ug/ml
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |