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產(chǎn)品名稱: PHOX2A antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
PHOX2A antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。PHOX2A antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
PHOX2A antibody
的詳細(xì)介紹
PHOX2A antibodyProduct Profile
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Product Name
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Rabbit anti-PHOX2A polyclonal antibody - N-terminal region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-PHOX2A antibody: synthetic peptide directed towards the N terminal of human PHOX2A
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PHOX2A antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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BovineDogPigRabbitRatZebra Fish
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Concentration
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1mg/ml
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Purification
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Affinity purified
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PHOX2A antibodyTarget Information
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Gene Symbol
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PHOX2A
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Gene Synonyms
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ARIX
CFEOM2
FEOM2
MGC52227
NCAM2
PMX2A
More
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Gene Full Name
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Paired-like homeobox 2a
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Gene Summary
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PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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Alternative Names
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ARIX
CFEOM2
FEOM2
MGC52227
NCAM2
PMX2A
More
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Molecular Weight(MW)
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30kDa
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Sequence
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284 amino acids
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PHOX2A antibodyDatabase Links
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Entrez Gene
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401
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SwissProt ID
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O14813
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Protein Accession
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NP_005160
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PHOX2A antibodyApplication
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Immunohistochemistry
Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-PHOX2A antibody
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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