EGFR (phospho Thr693) Antibody
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產(chǎn)品名稱: EGFR (phospho Thr693) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
EGFR (phospho Thr693) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。EGFR (phospho Thr693) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
EGFR (phospho Thr693) Antibody
的詳細(xì)介紹
EGFR (phospho Thr693) AntibodyProduct Profile
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Product Name
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EGFR (phospho Thr693) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.1) Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96 (19): 10869-10874Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255Noguchi T, et al. (1994) Mol Cell Biol; 14 (10): 6674-6682Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720
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Immunogen
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EGFR (Phospho-Thr693) antibody was raised against a peptide sequence around phosphorylation site of threonine 693 (P-L-T (p) -P-S) derived from Human EGFR.
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EGFR (phospho Thr693) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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EGFR (phospho Thr693) AntibodyTarget Information
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Gene Symbol
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EGFR
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Alternative Names
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ERBB
HER1
mENA
ERBB1
PIG61
GP3A
Receptor protein-tyrosine kinase ErbB-1
kinase EGFR
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Molecular Weight(MW)
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175 kDa
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Tissue Specificity
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This antibody detects endogenous level EGFR only when phosphorylated at threonine 693.
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EGFR (phospho Thr693) AntibodyDatabase Links
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Entrez Gene
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1956
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Protein Accession
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NP_005219.2
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EGFR (phospho Thr693) AntibodyApplication
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Application
Western blot analysis of lysed extracts from HUVEC cells untreated or treated with EGF using EGFR (Phospho-Thr693).
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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