ATF-2 (phospho Ser472) Antibody
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產(chǎn)品名稱: ATF-2 (phospho Ser472) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
ATF-2 (phospho Ser472) Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。ATF-2 (phospho Ser472) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
ATF-2 (phospho Ser472) Antibody
的詳細(xì)介紹
ATF-2 (phospho Ser472) AntibodyProduct Profile
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Product Name
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ATF-2 (phospho Ser472) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.1) Maekawa T., EMBO J. 8:2023-2028(1989).
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Immunogen
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ATF-2 (phospho Ser472) antibody was raised against a peptide sequence around phosphorylation site of Serine 472 (E-A-V (p)-A-T) derived from Human ATF-2.
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ATF-2 (phospho Ser472) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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IHC
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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ATF-2 (phospho Ser472) AntibodyTarget Information
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Gene Symbol
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ATF2
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Alternative Names
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Activating 2
ATF2
cAMP response element binding protein CRE- BP1
CREB2
HB16
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Molecular Weight(MW)
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54 kDa
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Tissue Specificity
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The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472.
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ATF-2 (phospho Ser472) AntibodyDatabase Links
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Entrez Gene
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1386
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Protein Accession
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NP_001243019.1
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ATF-2 (phospho Ser472) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using ATF-2 (Phospho-Ser472) antibody (left) or the same antibody preincubated with blocking peptide (right).
Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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