Estrogen Receptor-alpha (phospho Tyr537) Antibody
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產(chǎn)品名稱: Estrogen Receptor-alpha (phospho Tyr537) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Estrogen Receptor-alpha (phospho Tyr537) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Estrogen Receptor-alpha (phospho Tyr537) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Estrogen Receptor-alpha (phospho Tyr537) Antibody
的詳細(xì)介紹
Estrogen Receptor-alpha (phospho Tyr537) AntibodyProduct Profile
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Product Name
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Estrogen Receptor-alpha (phospho Tyr537) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.1) Sehime Temel, Endocrinology, Oct 2002; 143: 3974.
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Immunogen
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Estrogen Receptor-alpha (phospho Tyr537) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p)-D-L) derived from Human Estrogen Receptor-alpha.
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Estrogen Receptor-alpha (phospho Tyr537) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Estrogen Receptor-alpha (phospho Tyr537) AntibodyTarget Information
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Gene Symbol
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ESR1
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Alternative Names
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ER
ESR
ESR1
ESTR
NR3A1
More
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Molecular Weight(MW)
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66 kDa
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Tissue Specificity
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The antibody detects endogenous levels of ER-alpha only when phosphorylated at tyrosine 537.
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Estrogen Receptor-alpha (phospho Tyr537) AntibodyDatabase Links
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Entrez Gene
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2099
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Protein Accession
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NP_000116.2
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Estrogen Receptor-alpha (phospho Tyr537) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Estrogen Receptor-alpha (Phospho-Tyr537) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Application
Western blot analysis of extracts from K562 cells (Lane 2), using Estrogen Receptor-alpha (Phospho-Tyr537) Antibody. The lane on the left is treated with antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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