p70 S6 Kinase (phospho Thr389/412) Antibody
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產(chǎn)品名稱: p70 S6 Kinase (phospho Thr389/412) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
p70 S6 Kinase (phospho Thr389/412) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。p70 S6 Kinase (phospho Thr389/412) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
p70 S6 Kinase (phospho Thr389/412) Antibody
的詳細(xì)介紹
p70 S6 Kinase (phospho Thr389/412) AntibodyProduct Profile
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Product Name
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p70 S6 Kinase (phospho Thr389/412) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.1) Hong S, et al. (2014) J Biol Chem
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Immunogen
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p70 S6 Kinase (phospho Thr389/412) antibody was raised against a peptide sequence around phosphorylation site of threonine389/412 (G-F-T (p)-Y-V) derived from Human p70 S6 Kinase .
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p70 S6 Kinase (phospho Thr389/412) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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p70 S6 Kinase (phospho Thr389/412) AntibodyTarget Information
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Gene Symbol
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RPS6KB1
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Alternative Names
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KS6B1
P70-S6K
RPS6KB1
Ribosomal protein S6 kinase
polypeptide 1
More
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Molecular Weight(MW)
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70 kDa
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Tissue Specificity
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The antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at tyrosine 389/tyrosine 412.
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p70 S6 Kinase (phospho Thr389/412) AntibodyDatabase Links
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Entrez Gene
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6198
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Protein Accession
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NP_001258971.1
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p70 S6 Kinase (phospho Thr389/412) AntibodyApplication
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Application
Western blot analysis of extracts from Jurkat cells treated with Insulin using Phospho-p70 S6 Kinase (Thr389/412) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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