Raf1 (phospho Ser259) Antibody
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產(chǎn)品名稱: Raf1 (phospho Ser259) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Raf1 (phospho Ser259) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Raf1 (phospho Ser259) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Raf1 (phospho Ser259) Antibody
的詳細(xì)介紹
Raf1 (phospho Ser259) AntibodyProduct Profile
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Product Name
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Raf1 (phospho Ser259) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.1) Dougherty M K, et al. (2005) Mol Cell. 17 (2): 215-224. Hekman M, et al. (2005) FEBS Lett. 579 (2): 464-468. Avruch J, et al. (1994) Trends Biochem. Sci. 19, 279-283. Chong H, et al. (2001) EMBO J. 20, 3716-3727. King A J, et al. (1998) Nature. 396:180-183.
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Immunogen
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Raf1 (Phospho-Ser259) antibody was raised against a peptide sequence around phosphorylation site of serine 259 (S-T-S (p) -T-P) derived from Human Raf1.
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Raf1 (phospho Ser259) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Raf1 (phospho Ser259) AntibodyTarget Information
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Gene Symbol
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RAF1
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Alternative Names
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NS5
CRAF
Raf-1
c-Raf
BBC6
BCL2L8
C-RAF
C-Raf
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Molecular Weight(MW)
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73 kDa
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Tissue Specificity
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This antibody detects endogenous level of Raf-1 only when phosphorylated at serine 259.
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Raf1 (phospho Ser259) AntibodyDatabase Links
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Entrez Gene
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5894
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Protein Accession
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NP_002871.1
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Raf1 (phospho Ser259) AntibodyApplication
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Application
Western blot analysis of lysed extracts from 293 and MDA cells untreated or treated with PMA using Raf1 (Phospho-Ser259).
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1 (Phospho-Ser259).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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