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產(chǎn)品資料

CTNB1 Antibody

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產(chǎn)品名稱: CTNB1 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

CTNB1 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。CTNB1 Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


CTNB1 Antibody  的詳細(xì)介紹

CTNB1 AntibodyProduct Profile

Product Name CTNB1 Antibody
Antibody Type Primary Antibodies
Product description 
					

						The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.1) Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010)
					

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Immunogen 
This CTNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-673 amino acids from the C-terminal region of human CTNB1.

CTNB1 AntibodyKey Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IFIHC-PWB

For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

CTNB1 AntibodyTarget Information

Gene Symbol CTNNB1
Alternative Names
Catenin beta-1
Beta-catenin
CTNNB1
CTNNB
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Molecular Weight(MW) 85 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Drosophila

CTNB1 AntibodyDatabase Links

Entrez Gene 1499
Protein Accession P35222

CTNB1 AntibodyApplication

  • Application

    Confocal immunofluorescent analysis of CTNB1 Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

  • Application

    CTNB1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Application

    Western blot analysis of CTNB1 using rabbit polyclonal CTNB1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTNB1 gene.

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

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