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產(chǎn)品名稱: 14 3 3 zeta Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
14 3 3 zeta Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。14 3 3 zeta Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
14 3 3 zeta Antibody
的詳細(xì)介紹
14 3 3 zeta AntibodyProduct Profile
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Product Name
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14 3 3 zeta Antibody
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Antibody Type
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Primary Antibodies
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Product description
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This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.1) Gu YM, et al. (2006) FEBS Lett ; 580 (1): 305-310Powell DW, et al. (2003) Mol Cell Biol; 23 (15): 5376-5387Mackintosh C. (2004) Biochem J; 381 (Pt 2): 329-342.
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Immunogen
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14-3-3 zeta (Ab-58) antibody was raised against a peptide sequence around aa.56~60 (R-S-S-W-R) derived from Human 14-3-3 zeta.
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14 3 3 zeta AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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14 3 3 zeta AntibodyTarget Information
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Gene Symbol
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YWHAZ
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Molecular Weight(MW)
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28 kDa
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Tissue Specificity
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This antibody detects endogenous level of total 14-3-3 zeta protein.
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14 3 3 zeta AntibodyDatabase Links
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Entrez Gene
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7534
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Protein Accession
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NP_001129171.1
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14 3 3 zeta AntibodyApplication
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Application
(4μg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Similar results were obtained after antigen retrieval at pH 9.
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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