Keratin 18 (phospho Ser33) Antibody
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產(chǎn)品名稱: Keratin 18 (phospho Ser33) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Keratin 18 (phospho Ser33) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。Keratin 18 (phospho Ser33) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Keratin 18 (phospho Ser33) Antibody
的詳細(xì)介紹
Keratin 18 (phospho Ser33) AntibodyProduct Profile
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Product Name
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Keratin 18 (phospho Ser33) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. utations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.1) Ramaekers, F. C. and Bosman, F. T. (2004) J. Pathol. 204, 351-354. Chang, L. and Goldman, R. D. (2004) Nat. Rev. Mol. Cell Biol. 5, 601-613. Moll, R. et al. (1982) Cell 31, 11-24.
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Immunogen
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Keratin 18 (Phospho-Ser33) antibody was raised against a peptide sequence around phosphorylation site of serine 33 (A-A-S (p) -V-Y) derived from Human Keratin 18 (CK18).
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Keratin 18 (phospho Ser33) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Keratin 18 (phospho Ser33) AntibodyTarget Information
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Gene Symbol
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KRT18
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Alternative Names
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K18
CYK18
CBL2
RNF55
CK 18
CK18
Cytokeratin endo B
K18
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Molecular Weight(MW)
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46 kDa
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Tissue Specificity
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This antibody detects endogenous level of Keratin 18 only when phosphorylated at serine 33.
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Keratin 18 (phospho Ser33) AntibodyDatabase Links
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Entrez Gene
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3875
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Protein Accession
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NP_000215.1
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Keratin 18 (phospho Ser33) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Keratin 18 (Phospho-Ser33).
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Application
Western blot analysis of lysed extracts from HT29 cells untreated or treated with EGF using Keratin 18 (Phospho-Ser33).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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