IRS 1 (phospho Ser636) Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: IRS 1 (phospho Ser636) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
IRS 1 (phospho Ser636) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IRS 1 (phospho Ser636) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
IRS 1 (phospho Ser636) Antibody
的詳細介紹
IRS 1 (phospho Ser636) AntibodyProduct Profile
|
Product Name
|
IRS 1 (phospho Ser636) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit1) Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98 (8): 4640-4645Tzatsos A, et al. (2006) Mol Cell Biol; 26 (1): 63-76Kadowaki T, et al. (2000) J Clin Invest; 106 (4): 459-465Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98 (8): 4640-4645Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97 (5): 2355-2360
More
|
|
Immunogen
|
IRS-1 (Phospho-Ser636) antibody was raised against a peptide sequence around phosphorylation site of serine 636 (P-M-S (p) -P-K) derived from Human IRS-1.
|
IRS 1 (phospho Ser636) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
IHCWB
|
|
|
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
IRS 1 (phospho Ser636) AntibodyTarget Information
|
Gene Symbol
|
IRS1
|
|
Alternative Names
|
HIRS-1
CTNNB
OK/SW-cl.35
PRO2286
IRS-1
IRS1
More
|
|
Molecular Weight(MW)
|
180 kDa
|
|
Tissue Specificity
|
This antibody detects endogenous level of total IRS-1 protein.
|
IRS 1 (phospho Ser636) AntibodyDatabase Links
|
Entrez Gene
|
3667
|
|
Protein Accession
|
NP_005535.1
|
IRS 1 (phospho Ser636) AntibodyApplication
-
Application
Western blot analysis of lysed extracts from 3T3 cells untreated or treated with Insulin using IRS-1 (Phospho-Ser636).
-
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1 (Phospho-Ser636).
|
Application Notes
|
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
