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產(chǎn)品名稱: Mouse Mapk14 Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Mouse Mapk14 Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。Mouse Mapk14 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Mouse Mapk14 Antibody
的詳細(xì)介紹
Mouse Mapk14 AntibodyProduct Profile
Product Name
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Mouse Mapk14 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.1) Pan, W.W., et al. J. Biol. Chem. 285(45):34348-34354(2010)
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Immunogen
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This Mouse Mapk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14.
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Mouse Mapk14 AntibodyKey Feature
Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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WB
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For WB starting dilution is: 1:1000:
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Mouse Mapk14 AntibodyTarget Information
Gene Symbol
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Mapk14
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Alternative Names
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Mitogen-activated protein kinase 14
MAP kinase 14
MAPK 14
CRK1
Mitogen-activated protein kinase p38 alpha
MAP kinase p38 alpha
Mapk14
Crk1
Csbp1
Csbp2
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Molecular Weight(MW)
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41 kDa
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Sequence Similarities
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Predicted species reactivity based on immunogen sequence: Rat
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Mouse Mapk14 AntibodyDatabase Links
Entrez Gene
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26416
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Protein Accession
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P47811
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Mouse Mapk14 AntibodyApplication
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Application
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
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For WB starting dilution is: 1:1000:
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Additional Information
Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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