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產(chǎn)品資料

P38 MAPK Antibody

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產(chǎn)品名稱: P38 MAPK Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡(jiǎn)單介紹

P38 MAPK Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。P38 MAPK Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


P38 MAPK Antibody  的詳細(xì)介紹


P38 MAPK AntibodyProduct Profile

Product Name P38 MAPK Antibody
Antibody Type Primary Antibodies
Product description 
				

					Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.1) Ming Zheng, et al. (2005) The FASEB Journal. 19: 109-111Bernt van den et al. (2001) Blink Immunology, 166: 582-587Arshad Rahman, et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024Osamu Yoshino, et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241
				

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Immunogen 
P38 MAPK (Ab-182) antibody was raised against a peptide sequence around aa. 180~184 (T-G-Y-V-A) derived from Human P38 MAPK.

P38 MAPK AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

P38 MAPK AntibodyTarget Information

Gene Symbol MAPK14
Alternative Names
RK
p38
CSBP
EXIP
Mxi2
CSBP1
CSBP2
CSPB1
PRKM14
PRKM15
SAPK2A
p38ALPHA
MAPK2
MAPKAPK-2
MAPKAPK2
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Molecular Weight(MW) 43 kDa
Tissue Specificity This antibody detects endogenous level of total P38MAPK protein.

P38 MAPK AntibodyDatabase Links

Entrez Gene 1432
Protein Accession NP_001306.1

P38 MAPK AntibodyApplication

  • Application

    Western blot analysis of lysed extracts from 293 and HeLa cells using P38 MAPK (Ab-182).

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


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