Smad3 (phospho Thr179) Antibody
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產(chǎn)品名稱: Smad3 (phospho Thr179) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Smad3 (phospho Thr179) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Smad3 (phospho Thr179) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Smad3 (phospho Thr179) Antibody
的詳細(xì)介紹
Smad3 (phospho Thr179) AntibodyProduct Profile
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Product Name
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Smad3 (phospho Thr179) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.1) Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24
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Immunogen
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Smad3 (phospho Thr179) antibody was raised against a peptide sequence around phosphorylation site of threonine179 (P-E-T (p)-P-P) derived from Human Smad3 .
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Smad3 (phospho Thr179) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Smad3 (phospho Thr179) AntibodyTarget Information
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Gene Symbol
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SMAD3
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Alternative Names
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JV15-2
MAD-3
MADH3
Smad 3
Mothers against decapentaplegic homolog 3
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Molecular Weight(MW)
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50 kDa
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Tissue Specificity
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The antibody detects endogenous level of Smad3 only when phosphorylated at threonine 179.
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Smad3 (phospho Thr179) AntibodyDatabase Links
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Entrez Gene
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4088
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Protein Accession
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NP_001138574.1
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Smad3 (phospho Thr179) AntibodyApplication
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Application
Western blot analysis of extracts from HeLa cells treated with TNF using Phospho-Smad3 (Thr179) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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