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產(chǎn)品名稱: Cdc25A Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Cdc25A Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。Cdc25A Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Cdc25A Antibody
的詳細(xì)介紹
Cdc25A AntibodyProduct Profile
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Product Name
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Cdc25A Antibody
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Antibody Type
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Primary Antibodies
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Product description
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CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.1) Ito, Y., et al., Int. J. Mol. Med. 13(3):431-435 (2004).
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Immunogen
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This Cdc25A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human Cdc25A.
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Cdc25A AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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IHC-PWB
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For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50:
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Cdc25A AntibodyTarget Information
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Gene Symbol
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CDC25A
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Alternative Names
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M-phase inducer phosphatase 1
Dual specificity phosphatase Cdc25A
CDC25A
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Molecular Weight(MW)
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59 kDa
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Cdc25A AntibodyDatabase Links
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Entrez Gene
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993
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Protein Accession
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P30304
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Cdc25A AntibodyApplication
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Application
Western Blot at 1:2000 dilution + HCT116 whole cell lysate Lysates/proteins at 20 ug per lane.
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Application
Formalin-fixed and paraffin-embedded human Spleen tissue reacted with Cdc25A Antibody , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
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Application Notes
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For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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