IGF1R (phospho Tyr1346) Antibody
如果您對(duì)該產(chǎn)品感興趣的話(huà),可以
產(chǎn)品名稱(chēng): IGF1R (phospho Tyr1346) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
IGF1R (phospho Tyr1346) Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF1R (phospho Tyr1346) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IGF1R (phospho Tyr1346) Antibody
的詳細(xì)介紹
IGF1R (phospho Tyr1346) AntibodyProduct Profile
|
Product Name
|
IGF1R (phospho Tyr1346) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.1) Ullrich A., EMBO J. 5:2503-2512(1986).
More
|
|
Immunogen
|
IGF1R (phospho Tyr1346) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1346 (Q-P-Y (p)-A-H) derived from Human IGF1R .
|
IGF1R (phospho Tyr1346) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
IHC
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
IGF1R (phospho Tyr1346) AntibodyTarget Information
|
Gene Symbol
|
IGF1R
|
|
Alternative Names
|
CD221
kinase IGF1R
IGF1R
|
|
Molecular Weight(MW)
|
154 kDa
|
|
Tissue Specificity
|
The antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346.
|
IGF1R (phospho Tyr1346) AntibodyDatabase Links
|
Entrez Gene
|
3480
|
|
Protein Accession
|
NP_000866.1
|
IGF1R (phospho Tyr1346) AntibodyApplication
-
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF1R (Phospho-Tyr1346) antibody (left) or the same antibody preincubated with blocking peptide (right).
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
