Smad2 (phospho Ser250) Antibody
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產品名稱: Smad2 (phospho Ser250) Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
Smad2 (phospho Ser250) Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Smad2 (phospho Ser250) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Smad2 (phospho Ser250) Antibody
的詳細介紹
Smad2 (phospho Ser250) AntibodyProduct Profile
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Product Name
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Smad2 (phospho Ser250) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.1) Fransvea E, Mazzocca A, Antonaci S, Giannelli G (2009)Hepatology 49, 839-50 . Funaba M, Zimmerman CM, Mathews LS (2002)J Biol Chem 277, 41361-8. Kretzschmar M, Doody J, Timokhina I, Massagué J (1999)Genes Dev 13, 804-16 .
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Immunogen
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Smad2 (phospho Ser250) antibody was raised against a peptide sequence around phosphorylation site of serine250 (E-L-S (p)-P-T) derived from Human Smad2 .
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Smad2 (phospho Ser250) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Smad2 (phospho Ser250) AntibodyTarget Information
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Gene Symbol
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SMAD2
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Alternative Names
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JV18-1
MADH2
Mad-related protein 2
Mothers against DPP homolog 2
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Molecular Weight(MW)
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65 kDa
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Tissue Specificity
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The antibody detects endogenous level of Smad2 only when phosphorylated at serine 250.
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Smad2 (phospho Ser250) AntibodyDatabase Links
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Entrez Gene
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4087
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Protein Accession
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NP_001003652.1
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Smad2 (phospho Ser250) AntibodyApplication
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Application
Western blot analysis of extracts from 293 cells treated with PMA using Phospho-Smad2 (Ser250) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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