a Synuclein (phospho Ser129) Antibody
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產(chǎn)品名稱: a Synuclein (phospho Ser129) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
a Synuclein (phospho Ser129) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。 a Synuclein (phospho Ser129) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
a Synuclein (phospho Ser129) Antibody
的詳細介紹
a Synuclein (phospho Ser129) AntibodyProduct Profile
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Product Name
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a Synuclein (phospho Ser129) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.1) Takahashi T, et al. J Biol Chem 2003 Oct 24; 278 (43): 42225-33Ahn BH, et al. J Biol Chem 2002 Apr 05; 277 (14): 12334-42Negro A, et al. FASEB J 2002 Feb; 16 (2): 210-2Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119.
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Immunogen
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a-Synuclein (Phospho-Ser129) antibody was raised against a peptide sequence around phosphorylation site of serine 129 (M-P-S (p) -E-E) derived from Human α-Synuclein.
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a Synuclein (phospho Ser129) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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a Synuclein (phospho Ser129) AntibodyTarget Information
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Gene Symbol
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SNCA
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Alternative Names
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PD1
NACP
PARK1
PARK4
ERBB
ERBB1
HER1
SYN
SYUA
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Molecular Weight(MW)
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18 kDa
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Tissue Specificity
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This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 1214.
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a Synuclein (phospho Ser129) AntibodyDatabase Links
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Entrez Gene
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6622
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Protein Accession
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NP_000336.1
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a Synuclein (phospho Ser129) AntibodyApplication
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Application
Western blot analysis of lysed extracts from mouse brain tissue using α-Synuclein (Phospho-Ser129).
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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