Elk1 (phospho Ser389) Antibody
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產(chǎn)品名稱: Elk1 (phospho Ser389) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Elk1 (phospho Ser389) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Elk1 (phospho Ser389) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Elk1 (phospho Ser389) Antibody
的詳細(xì)介紹
Elk1 (phospho Ser389) AntibodyProduct Profile
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Product Name
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Elk1 (phospho Ser389) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene1) Janknecht R, et al. (1993) EMBO J. 12 (13): 5097-5104. Marais R, et al. (1993) Cell 73:381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14:4815-4824. Hill C S, et al. (1995) Cell. 80:199-211. Cavigelli M, et al. (1995) EMBO J. 14:5957-5964.
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Immunogen
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Elk1 (Phospho-Ser389) antibody was raised against a peptide sequence around phosphorylation site of serine 389 (P-R-S (p) -P-A) derived from Human Elk-1.
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Elk1 (phospho Ser389) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Elk1 (phospho Ser389) AntibodyTarget Information
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Gene Symbol
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ELK1
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Alternative Names
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SUI1
ELK1
ETS-domain protein Elk-1
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Molecular Weight(MW)
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62 kDa
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Tissue Specificity
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This antibody detects endogenous level of Elk1 only when phosphorylated at serine 389.
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Elk1 (phospho Ser389) AntibodyDatabase Links
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Entrez Gene
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2002
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Protein Accession
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NP_001107595.1
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Elk1 (phospho Ser389) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk1 (Phospho-Ser389).
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Application
Western blot analysis of lysed extracts from HT29 cells untreated or treated with Anisomycin using Elk1 (Phospho-Ser389).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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