SYK (phospho Tyr352) Antibody
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產(chǎn)品名稱: SYK (phospho Tyr352) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
SYK (phospho Tyr352) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。SYK (phospho Tyr352) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
SYK (phospho Tyr352) Antibody
的詳細(xì)介紹
SYK (phospho Tyr352) AntibodyProduct Profile
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Product Name
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SYK (phospho Tyr352) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion1) Yagi S., Biochem. Biophys. Res. Commun. 200:28-34(1994).
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Immunogen
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SYK (phospho Tyr352) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 352 (S-P-Y (p)-A-D) derived from Human SYK.
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SYK (phospho Tyr352) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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SYK (phospho Tyr352) AntibodyTarget Information
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Gene Symbol
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SYK
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Alternative Names
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SYK
KSYK
FLJ25043
FLJ37489
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Molecular Weight(MW)
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72 kDa
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Tissue Specificity
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The antibody detects endogenous levels of SYK only when phosphorylated at tyrosine 352.
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SYK (phospho Tyr352) AntibodyDatabase Links
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Entrez Gene
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6850
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Protein Accession
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NP_001167638.1
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SYK (phospho Tyr352) AntibodyApplication
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Application
Western blot analysis of extracts from HuvEc cells (Lane 2) and HepG2 cells (Lane 3), using SYK (Phospho-Tyr352) Antibody. The lane on the left is treated with antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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