CDC2 (phospho Thr161) Antibody
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產(chǎn)品名稱: CDC2 (phospho Thr161) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
CDC2 (phospho Thr161) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。CDC2 (phospho Thr161) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
CDC2 (phospho Thr161) Antibody
的詳細介紹
CDC2 (phospho Thr161) AntibodyProduct Profile
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Product Name
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CDC2 (phospho Thr161) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.1) Ukomadu C, et al. (2003) J Biol Chem; 278 (7): 4840-6. Morris MC, et al. (2002) J Biol Chem; 277 (26): 23847-53. Brown NR, et al. (1999) J Biol Chem; 274 (13): 8746-56. Liu Y, et al. (2004) J Biol Chem; 279 (6): 4507-14.
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Immunogen
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CDC2 (Phospho-Thr161) antibody was raised against a peptide sequence around phosphorylation site of threonine161 (T-Y-T (p) -H-E) derived from Human CDC2.
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CDC2 (phospho Thr161) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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CDC2 (phospho Thr161) AntibodyTarget Information
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Gene Symbol
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CDK1
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Alternative Names
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CDC2
CDC28A
P34CDC2
C1orf215
LAP18
OP18
CDC28
CDC2A
CDK1
Cyclin-dependent kinase 1
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Molecular Weight(MW)
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34 kDa
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Tissue Specificity
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This antibody detects endogenous level of CDC2 only when phosphorylated at threonine 161.
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CDC2 (phospho Thr161) AntibodyDatabase Links
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Entrez Gene
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983
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Protein Accession
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NP_001163877.1
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CDC2 (phospho Thr161) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CDC2 (Phospho-Thr161).
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Application
Western blot analysis of lysed extracts from HeLa cells untreated (Lane 1) or treated with UV (lane 2) using CDC2 (Phospho-Thr161).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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