IKK- gamma (phospho Ser31) Antibody
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產(chǎn)品名稱(chēng): IKK- gamma (phospho Ser31) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
IKK- gamma (phospho Ser31) Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。IKK- gamma (phospho Ser31) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IKK- gamma (phospho Ser31) Antibody
的詳細(xì)介紹
IKK- gamma (phospho Ser31) AntibodyProduct Profile
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Product Name
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IKK- gamma (phospho Ser31) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly.1) Carter RS, Pennington KN, Ungurait BJ, Ballard DW (2003)J Biol Chem 278, 19642-8.
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Immunogen
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IKK- gamma (phospho Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine 31 (E-E-S (p)-P-L) derived from Human IKK-gamma.
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IKK- gamma (phospho Ser31) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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IKK- gamma (phospho Ser31) AntibodyTarget Information
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Gene Symbol
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IKBKG
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Alternative Names
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FIP-3
FIP3
I-kappa-B kinase gamma
IKBKG
IKKAP1
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Molecular Weight(MW)
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48 kDa
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Tissue Specificity
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The antibody detects endogenous level of IKK- gamma only when phosphorylated at serine 31.
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IKK- gamma (phospho Ser31) AntibodyDatabase Links
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Entrez Gene
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8517
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Protein Accession
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NP_001093326.2
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IKK- gamma (phospho Ser31) AntibodyApplication
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Application
Western blot analysis of extracts from 293 cells treated with TNF-a using Phospho-IKK- gamma (Ser31) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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