Cyclin D1 (phospho Ser90) Antibody
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產(chǎn)品名稱: Cyclin D1 (phospho Ser90) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Cyclin D1 (phospho Ser90) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Cyclin D1 (phospho Ser90) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
Cyclin D1 (phospho Ser90) Antibody
的詳細介紹
Cyclin D1 (phospho Ser90) AntibodyProduct Profile
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Product Name
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Cyclin D1 (phospho Ser90) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.1) Sewing A, Müller R (1994) Oncogene 9, 2733-6
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Immunogen
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Cyclin D1 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of serine 90 (F-L-S (p)-L-E) derived from Human Cyclin D1 .
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Cyclin D1 (phospho Ser90) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Cyclin D1 (phospho Ser90) AntibodyTarget Information
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Gene Symbol
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CCND1
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Alternative Names
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BCL1
CCND1
CYL-1
PRAD1
PRAD1 oncogene
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Molecular Weight(MW)
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31 kDa
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Tissue Specificity
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The antibody detects endogenous level of Cyclin D1 only when phosphorylated at serine 90.
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Cyclin D1 (phospho Ser90) AntibodyDatabase Links
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Entrez Gene
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595
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Protein Accession
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NP_444284.1
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Cyclin D1 (phospho Ser90) AntibodyApplication
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Application
Western blot analysis of extracts from K562 tissue using Cyclin D1 (Phospho-Ser90) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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