HSF1 Sumoylation Site Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: HSF1 Sumoylation Site Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
HSF1 Sumoylation Site Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。HSF1 Sumoylation Site Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
HSF1 Sumoylation Site Antibody
的詳細(xì)介紹
HSF1 Sumoylation Site AntibodyProduct Profile
|
Product Name
|
HSF1 Sumoylation Site Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.1) Hilgarth, et al., Biochem Biophys Res Commun. 2003 Mar 28;303(1):196-200.
More
|
|
Immunogen
|
This HSF1 Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from human HSF1 Sumoylation Site.
|
HSF1 Sumoylation Site AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
Ig
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
IFWB
|
|
|
For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
|
|
Species Reactivity
|
HumanMouse
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Unpurified
|
HSF1 Sumoylation Site AntibodyTarget Information
|
Gene Symbol
|
HSF1
|
|
Alternative Names
|
Heat shock factor protein 1
HSF 1
Heat shock transcription factor 1
HSTF 1
HSF1
HSTF1
More
|
|
Molecular Weight(MW)
|
57 kDa
|
|
Sequence Similarities
|
Predicted species reactivity based on immunogen sequence: Bovine
|
HSF1 Sumoylation Site AntibodyDatabase Links
|
Entrez Gene
|
3297
|
|
Protein Accession
|
Q00613
|
HSF1 Sumoylation Site AntibodyApplication
-
Application
Western blot analysis in Jurkat cell line and mouse heart tissue lysates (35ug/lane).
-
Application
Confocal immunofluorescent analysis of HSF1 Sumoylation Site Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
|
Application Notes
|
For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
|
|
Storage Buffer
|
Supplied in PBS with 0.09% (W/V) sodium azide.
|
