Abl (phospho Tyr204) Antibody
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產(chǎn)品名稱: Abl (phospho Tyr204) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Abl (phospho Tyr204) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Abl (phospho Tyr204) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
Abl (phospho Tyr204) Antibody
的詳細介紹
Abl (phospho Tyr204) AntibodyProduct Profile
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Product Name
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Abl (phospho Tyr204) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins).1) Meyn MA, et al. (2006) J Biol Chem 281, 30907-16
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Immunogen
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Abl (phospho Tyr204) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y (p)-V-S) derived from Human c-Abl.
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Abl (phospho Tyr204) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Abl (phospho Tyr204) AntibodyTarget Information
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Gene Symbol
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ABL1
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Alternative Names
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p150
c-ABL
EC 2.7.10.2
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Molecular Weight(MW)
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135 kDa
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Tissue Specificity
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The antibody detects endogenous level of Abl only when phosphorylated at tyrosine 204.
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Abl (phospho Tyr204) AntibodyDatabase Links
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Entrez Gene
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25
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Protein Accession
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NP_005148.2
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Abl (phospho Tyr204) AntibodyApplication
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Application
Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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