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產(chǎn)品資料

CASP3 Antibody

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產(chǎn)品名稱: CASP3 Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

CASP3 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。CASP3 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


CASP3 Antibody  的詳細(xì)介紹

CASP3 AntibodyProduct Profile

Product Name CASP3 Antibody
Antibody Type Primary Antibodies
Product description 
					

						CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.1) Selvakumar, P., et al., (2006) FEBS Lett. 580 (8), 2021-2026.
					

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Immunogen 
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CASP3.

CASP3 AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAWB

CASP3 antibody can be used for detection of CASP3 by ELISA at 1:62500. CASP3 antibody can be used for detection of CASP3 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

Human

Concentration 1mg/ml
Purification Protein A

CASP3 AntibodyTarget Information

Gene Symbol CASP3
Alternative Names
CASP3
CPP32
SCA-1
CPP32B
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Molecular Weight(MW) 32 kDa, 32 kDa

CASP3 AntibodyDatabase Links

Entrez Gene 836
Protein Accession NP_004337

CASP3 AntibodyApplication

  • Application

    Antibody used in IHC on rat and mouse.

  • Application

    Antibody used in WB on Human Liver at 5 ug/ml.

Positive Control 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Application Notes
CASP3 antibody can be used for detection of CASP3 by ELISA at 1:62500. CASP3 antibody can be used for detection of CASP3 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4?C. For longer periods of storage, store CASP3 antibody at -20?C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

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